2022 Mercedes-Benz E-Class

The 2022 Mercedes-Benz E-Class is listed in 11 versions in the EPA fuel economy database, with 2.0 L 4-cyl turbo, 3.0 L 6-cyl hybrid and 3.0 L 6-cyl turbo hybrid powertrains. Combined fuel economy ranges from 22 to 26 MPG (best: 9.0 L/100 km).

Model year2022
Versions11
ClassMidsize Cars, Midsize Station Wagons, Subcompact Cars
Drive4-Wheel Drive, All-Wheel Drive, Rear-Wheel Drive

Engines, transmissions & fuel economy

VersionPowertrainTransmissionDriveFuelMPG city / hwy / combL/100 km (comb)CO2 g/miClass
AMG E53 4matic Plus3.0 L 6-cyl hybridAutomatic 9-spd4-Wheel DrivePremium21 / 29 / 249.8373Midsize Cars
AMG E53 4matic Plus Convertible3.0 L 6-cyl hybridAutomatic 9-spd4-Wheel DrivePremium20 / 27 / 2210.7397Subcompact Cars
AMG E53 4matic Plus Coupe3.0 L 6-cyl hybridAutomatic 9-spd4-Wheel DrivePremium20 / 28 / 2310.2384Subcompact Cars
E3502.0 L 4-cyl turboAutomatic 9-spdRear-Wheel DrivePremium23 / 31 / 269.0342Midsize Cars
E350 4matic2.0 L 4-cyl turboAutomatic 9-spdAll-Wheel DrivePremium21 / 29 / 249.8366Midsize Cars
E450 4matic3.0 L 6-cyl turbo hybridAutomatic 9-spd4-Wheel DrivePremium23 / 30 / 259.4348Midsize Cars
E450 4matic All-Terrain (wagon)3.0 L 6-cyl turbo hybridAutomatic 9-spd4-Wheel DrivePremium21 / 28 / 249.8368Midsize Station Wagons
E450 4matic Convertible3.0 L 6-cyl turbo hybridAutomatic 9-spd4-Wheel DrivePremium22 / 29 / 249.8362Subcompact Cars
E450 4matic Coupe3.0 L 6-cyl turbo hybridAutomatic 9-spd4-Wheel DrivePremium21 / 30 / 249.8362Subcompact Cars
E450 Convertible3.0 L 6-cyl turbo hybridAutomatic 9-spdRear-Wheel DrivePremium22 / 29 / 259.4360Subcompact Cars
E450 Coupe3.0 L 6-cyl turbo hybridAutomatic 9-spdRear-Wheel DrivePremium22 / 29 / 259.4360Subcompact Cars

Figures are EPA estimates for the U.S. market (U.S. gallons). Your mileage will vary. Transmissions: (S6) = 6-speed with manual select mode, (AV) = continuously variable, (AM) = automated manual.

Safety recalls

Check the NHTSA recall database for the 2022 Mercedes-Benz E-Class.

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