2021 Mercedes-Benz E-Class

The 2021 Mercedes-Benz E-Class is listed in 13 versions in the EPA fuel economy database, with 2.0 L 4-cyl turbo, 3.0 L 6-cyl hybrid, 3.0 L 6-cyl turbo hybrid and 4.0 L 8-cyl turbo powertrains. Combined fuel economy ranges from 18 to 26 MPG (best: 9.0 L/100 km).

Model year2021
Versions13
ClassMidsize Cars, Midsize Station Wagons, Subcompact Cars
Drive4-Wheel Drive, Rear-Wheel Drive

Engines, transmissions & fuel economy

VersionPowertrainTransmissionDriveFuelMPG city / hwy / combL/100 km (comb)CO2 g/miClass
AMG E53 4matic Plus3.0 L 6-cyl hybridAutomatic 9-spd4-Wheel DrivePremium22 / 29 / 259.4361Midsize Cars
AMG E53 4matic Plus Convertible3.0 L 6-cyl hybridAutomatic 9-spd4-Wheel DrivePremium21 / 27 / 2310.2384Subcompact Cars
AMG E53 4matic Plus Coupe3.0 L 6-cyl hybridAutomatic 9-spd4-Wheel DrivePremium21 / 28 / 249.8378Subcompact Cars
AMG E63 S 4matic Plus4.0 L 8-cyl turboAutomatic 9-spd4-Wheel DrivePremium16 / 23 / 1813.1484Midsize Cars
AMG E63 S 4matic Plus (SW)4.0 L 8-cyl turboAutomatic 9-spd4-Wheel DrivePremium16 / 23 / 1813.1483Midsize Station Wagons
E3502.0 L 4-cyl turboAutomatic 9-spdRear-Wheel DrivePremium22 / 31 / 259.4349Midsize Cars
E350 4matic2.0 L 4-cyl turboAutomatic 9-spd4-Wheel DrivePremium22 / 30 / 259.4355Midsize Cars
E450 4matic3.0 L 6-cyl turbo hybridAutomatic 9-spd4-Wheel DrivePremium23 / 30 / 269.0349Midsize Cars
E450 4matic All-Terrain (wagon)3.0 L 6-cyl turbo hybridAutomatic 9-spd4-Wheel DrivePremium22 / 28 / 249.8364Midsize Station Wagons
E450 4matic Convertible3.0 L 6-cyl turbo hybridAutomatic 9-spd4-Wheel DrivePremium23 / 29 / 259.4353Subcompact Cars
E450 4matic Coupe3.0 L 6-cyl turbo hybridAutomatic 9-spd4-Wheel DrivePremium23 / 30 / 259.4350Subcompact Cars
E450 Convertible3.0 L 6-cyl turbo hybridAutomatic 9-spdRear-Wheel DrivePremium23 / 30 / 259.4349Subcompact Cars
E450 Coupe3.0 L 6-cyl turbo hybridAutomatic 9-spdRear-Wheel DrivePremium23 / 31 / 269.0341Subcompact Cars

Figures are EPA estimates for the U.S. market (U.S. gallons). Your mileage will vary. Transmissions: (S6) = 6-speed with manual select mode, (AV) = continuously variable, (AM) = automated manual.

Safety recalls

Check the NHTSA recall database for the 2021 Mercedes-Benz E-Class.

Tools for this car