Toyota Sienna vs Honda Odyssey
2026 Toyota Sienna vs 2026 Honda Odyssey: powertrains, fuel economy and running costs side by side. The most efficient Toyota Sienna version is rated 36 MPG combined, against 22 MPG for the best Honda Odyssey.
| 2026 Toyota Sienna | 2026 Honda Odyssey | |
|---|---|---|
| Versions rated | 2 | 1 |
| Class | Minivan - 2WD, Minivan - 4WD | Minivan - 2WD |
| Powertrains | 2.5 L 4-cyl hybrid | 3.5 L 6-cyl |
| Transmissions | Automatic (AV-S6) | Automatic (S10) |
| Drive | All-Wheel Drive, Front-Wheel Drive | Front-Wheel Drive |
| Combined fuel economy | 35–36 MPG | 22 MPG |
| Best L/100 km | 6.5 | 10.7 |
| EV range (best) | — | — |
| Lowest CO2 (g/mi) | 246 | 395 |
| EPA annual fuel cost (from) | $1,850 | $3,050 |
EPA estimates for the U.S. market. The EPA annual fuel cost assumes 15,000 miles a year (45% highway, 55% city) at national average fuel prices. Use the comparison tool with your own distance and prices.